Tuesday, January 19, 2010

Choices: Graduate program edition

It's that time of year. The applications are in. Undergraduates (and others) around the country are waiting to hear if they've been accepted or invited for an interview. In less than three months, they will have decided where to spend the next 3 to 7 years. Between now and then, they will be gathering intel--scouring websites, talking with PIs and students, visiting campuses--which will inform their impending decision.

The whole process can be overwhelming. I was pretty clueless going in. I knew I wanted to pursue biological chemistry research. I had found professors whose research I was interested in. Beyond that, I didn't know what to expect or what I was looking for in a graduate program.

My undergraduate training was at a mid-sized state school in a small department, which encompassed chemistry and biochemistry. My experience and interactions there certainly influenced my views of what I wanted. I gravitated toward programs that had a similar atmosphere. This meant programs that were highly collaborative and multi-disciplinary in practice. I was weary of departments and labs in which PIs talked about collaborations with people across the country or half way around the world, but never mentioned working with colleagues in the department. I recently described my philosophy regarding divisions between disciplines and subfields of chemistry and biology, a philosophy I held even as a prospective Ph.D. student. I felt then (and still do) that it is difficult to integrate and advance related disciplines if a department imposes rigid barriers between them. I realized later that the rigid structure often went along with a seeming lack of collaboration within the department. I also stayed away from programs in which there seemed to be a great deal of tension between students and their PIs. This was largely rooted in a lack of self-confidence. I could not envision myself going head-to-head with an adviser on a regular basis, nor could I imagine being silent or deferential during repetitive conflicts, especially those unrelated to research. I also could not see myself doing well in a cutthroat department.

I heeded the advice of my undergrad professors. Dr. D told me to find the student who had been in the program the longest, who would have the most experience with the program, the most reason to be bitter, and usually the most honest responses. If you talk to that person and he or she doesn't regret joining the program, then that's a good sign. I did just this on my visit to PSU. Someone else suggested asking basically everyone I met about the typical length of a Ph.D. in their program and how long they had been there. In chemistry, an average beyond five years was viewed as problematic. An issue that revealed itself was that many programs stop providing funding to students after six years; in some of the same programs, it was not unusual to take that long or longer to complete a Ph.D.

Dr. K, another undergrad instructor, counseled me to not pick a program if there were not at least two advisers that I could see myself working for. Although Bear was my first choice for mentor, I saw the wisdom of this advice play out in my program. There are several reasons you might (have to) pass on your first choice PI. You might realize that you'd rather be mauled by hyenas than work for your "dream" adviser once you do a rotation in his/her lab. A PI's funding situation may not allow him/her to take a new student the year you arrive; hopefully this is something you would know before choosing a program, but there is no guarantee. If the PI has a tenure review and doesn't get it, he/she may choose to go somewhere else. Or there may be a high level of interest in a given subfield the year you join. Among my first year colleagues, there were 8 people vying for 6 spots in three labs. Needless to say, two didn't get into the labs they wanted. One of them found a suitable alternative; the other postponed joining a lab for almost another year. The point is things happen, so it's good to have more than one option.

Looking back, perhaps one of the most important things about the application process was figuring out what I really wanted. The questions I asked myself were just as important as the ones I asked others. What was most important to me: sexy science or sanity? What was I willing to compromise on? Was an ultra-competitive or a collaborative environment right for me? I spent time thinking about my experience and my level of comfort and confidence. As a prospective grad student, I didn't have much of any of those. I chose the program where I could see myself succeeding at research that excited, where I would learn from my instructors, my adviser, and other labs. It was a good program--a great one in my book, actually--but not the "best" of my choices (at least according to the U.S. News and World Report). But in hindsight, it was the best program from me. I went in as a timid undergrad but left as a confident scientist. And that's what it should really be about.


Monday, January 18, 2010

The future of the Scientiae carnival

Scientiae is facing a crisis--where does it go from here.

If you're new to the blogosphere (and maybe even if you're not), Scientiae is a monthly carnival built around stories of and from women in STEM. It's been going for three years now, but of late, contributions have been dropping off. So what is to become of Scientiae? skookumchick writes:
So the question arises: is there still value to having Scientiae? Or should we shut it down as a great community-building tool whose time has come to be let go?
Several bloggers, including myself, would like to see it continue. Among the commenters, there are enough volunteers for hosting to cover almost the entire year. But jokerine comments:
The trouble is, just wanting to read it isn't enough. I want to read it too, but I hardly contribute anymore and I was a horrible host. Hosting isn't any fun if there are no submissions.
Carnivals die without contributions. In response, I have pledged to contribute to the carnival at least seven times in the next year, should it continue. I chose this number because of my blogging frequency and my interest in previous carnival topics. I also want to point out that, even though the focus of the carnival is women in STEM, anyone is invited to contribute. Learn more about the carnival, then voice, er type, your opinion about the fate of Scientiae. Personally I hope we can keep this community carnival going :)

Saturday, January 16, 2010

Put on your game face

Bright-eyed and bushy-tailed, most new grad students have a fairly altruistic view of science, even if they hold a more cynical view of the world at large. When you are just starting down that path toward a career in science, you often think only one thing should matter: the science. You are convinced that this is what you'll spend the vast majority of your time doing; that science will be the sole focus of you, your peers, your superiors, your collaborators; that as you advance in your career, you will be evaluated on the quality of that science.

Here's the thing about science: It's done by humans, which means human nature enters into the equation. There are two dicta of human interactions, which complicate things:
  • Where two or more people are gathered together, there also shall be disagreement.
  • Where four or more people are gathered together, there also shall be factions.
There may be exceptions (but I'm doubtful). In my experience though, anytime you get a group of people together, even if working for a common purpose, politics enter the picture--even in science. chall's post on work politics she's dealing with really got me to thinking about this. The politics don't stop at the lab; they extend into departments, institutes, entire fields of science. How we engage, how we react can impact our careers. It sometimes comes down to how we play the game.

Navigating politics can be a challenge. If you're new to a lab, the dividing line is not always clear, as chall points out. Honestly, this may not be a bad thing; it's easier to stay out of the politics in this situation. Being a veteran in a lab is not always beneficial because the politics can bog you down. They can sap a lot of energy and focus out of you that would be best spent on other things. Trust me. I went there in Bear's lab; it was exhausting and infuriating. There reached a point when things in my life outside of the lab were taking so much energy that I couldn't afford to put any more into frustrated factions. I was far more focused when that happened.

This does not mean we can completely ignore the politics of science and units therein, but we do have to learn the rules of the game and how to choose our battles. Here are a few things I've interpreted from experience and observation during my relatively short time in science (in no particular order):
  • If you're at an early career stage, tread carefully, but...
  • Occasionally you have to show someone that you will not be his/her doormat.
  • You can get by with a lot until you piss off one of these people: the lab manager, the lab admin, or the PI.
  • Try not to burn bridges. Any given field of science is a small world after all. You never know when you might be working with/near/for someone you thought you'd never see again.
  • You have to be seen. In a meeting with grad students following a seminar at PSU, Ben Cravatt shared one lesson he wished he had learned before starting his independent career. He commented that he thought working hard and doing great science would be enough to get the high profile publications and funding. He realized shortly thereafter that he had to be seen; he needed to go to meetings and present his work, so that he could connect with the people that would be reviewing his manuscripts and grants and begin to establish name recognition. In short, build a network.
To an extent, grad students and postdocs are insulated from the politics of their institutes and fields, which places a definite limitation on the list I provide here. Add to this, that every department and field has its own culture and political climate. The rules of play vary widely, but in academia, those who have successful independent careers learned to navigate the political landscape without falling off a cliff. We have to do good science, but we also have to learn to play the game.

Friday, January 15, 2010

Question for readers

Anyone have a recommendation for a decent mouse anatomy reference? If so, leave a comment please! I would prefer an eBook but, if you're aware of a good print reference, I'll take that too.

Wednesday, January 13, 2010

Now, for something completely different...

It's been a while since I really talked about my life and research without whining. At the end of 2009, I was in a bit of a slump. Paramed and I were both stressed. My stress was due to lack of research progress, his due to work insanity and finals. And then there were the holidays. We were stressed out, eating junk food, not exercising, and otherwise behaving like slobs.

We've been trying to change our habits this month. We're getting up earlier. We're eating healthier foods. We've worked out every day. These things along have improved our moods and energy level. Paramed has started working in a biochem lab where he is working on his B.S. in biochem (yes, I'm a terrible influence :P), where he's been doing protein purification this week (prior to the start of classes). He seems to be enjoying it.

And I am having a blast in the lab these days. After we returned from holiday travels, I started learning all sorts of new things. The focus of my project has shifted from an in vitro model, which we have not successfully validated, to an in vivo model. The in vivo model has been characterized and is used by some collaborators in a very different context. There are many questions remaining that are of great interest to Guru and me. I've never done in vivo studies, but this was a major thing that I wanted to learn in my postdoc. Now I'm doing it. Even better, we can use intravital microscopy in this model, which (1) has not been used in this model, (2) has the potential to unmask kinetics of events, (3) is just plain sexy, and (4) gives me the chance to work with a colleague that I get on with really well. After basically an aggregate week of training with said colleague, I'm flying solo. Keep in mind this is all new to me, so I can't believe that I'm doing small animal surgery and imaging. We started running preliminary experiments this week. There are still a lot of data and samples to process, but things are looking promising. And Guru is quite excited about developing the model for intravital microscopy. So things are good, despite working late and spending most of my time this week alone in a cold, dark, windowless room and not having much time to eat lunch... or in this case tonight, dinner*. I'm actually enjoying it! I'm excited about my research!! A great way to start a new year. Hopefully this will set the tone for the months to come.

*If I fail to make sense here, I blame the sensory deprivation, lack of food, or lack of human contact... or some combination of the three :)